Ursolic Acid

Basic Information:

Product Name: Ursolic Acid

Specification: 25%-98%

CAS: 77-52-1

Plant Source: Bearberry leaf / Rosemary

Package:1g-5kg (aluminum foil bag), 5KG-25KG (carton), over 25kg (cardboard drum)

Sample: 50g

Transportation Method: Express, Air, Sea

Payment Method: Bank transfer, Western Union, Paypal

Product Description:

Ursolic acid is an organic compound with the molecular formula C30H48O3. It is a natural triterpene carboxylic acid compound, which has preventive and anticancer activities and can be used as the emulsifier of drugs and food. It is found in many plants such as prunella, bear fruit and leaves. Extraction of ursolic acid by ethanol and methanol The extraction of ursolic acid is generally carried out by ethanol and methanol, and then the extract is separated and purified. One method is to concentrate the extract under pressure and use petroleum ether, chloroform and ethyl acetate for extraction separation. The other is to decompress and concentrate the extract, and separate and enrich with silica gel column or crosslinked dextran gel column. With this process, the column packing cost is high, the process is complicated, and toxic organic solvent is often used as elution agent, polluting the environment. In addition, macroporous resin was used to separate the extract. In the process of extracting ursolic acid from bear fruit leaves by precipitation-adsorption method, bear fruit leaves were first extracted with ethanol, and the extract was alkalized to pH value of about 10.96 with 10% NaOH solution, and impurities such as polyphenols were removed by filtration. After precipitation, the filtrate was acidified to pH value of 4.00 with 10% sulfuric acid. Then diluted with the same volume of pH 4.00 acid aqueous solution, ursolic acid precipitated crude product was obtained. After the crude product was dissolved in methanol, pH value of the sample solution was adjusted to 7.07, and pH value of the eluent was adjusted to 11.0. The eluent was adsorbed with D-type macroporous resin and eluted step by step. The eluent of 90% ethanol solution was collected and concentrated and crystallized to obtain ursolic acid products. The purity of the product was 90.23%, the recovery was 98.02%, and the total recovery was 89.09%.

Applications:

This product is used in the manufacture of health care products and health food and research institutions (not suitable for direct consumption by individuals)